SEC Form 4
Axsome Therapeutics, Inc (AXSM) insider trading
In the 12 months to Oct 23, 2026, 6 AXSM insiders reported open-market sales of $133.9M across 17 filings; no open-market purchases were filed.
Latest filing · Last 12 months · Source: SEC EDGAR · How we count
- Open-market sales
- $133.9M
- 17 filings · 6 insiders
- Open-market purchases
- $0
- 0 filings
- Pre-arranged sales (10b5-1)
- 17 of 17
- All $133.9M sold was pre-arranged
Who traded AXSM, and when
- Sale
- Sale, pre-arranged (10b5-1)
AXSM daily close from Oct 23, 2025 to Oct 22, 2026, between $127.06 and $255.17, last $156.07. 17 sale and 0 purchase filings by 6 insiders, marked at their filing dates. Herriot Tabuteau, Chief Executive Officer: sold $97.8M across 7 filings, first filed Nov 5, 2025, last Aug 7, 2026. Nick Pizzie, Chief Financial Officer: sold $10.2M across 2 filings, first filed Jan 23, 2026, last Jun 9, 2026. Mark L. Jacobson, Chief Operating Officer: sold $8.9M across 3 filings, first filed Feb 27, 2026, last Sep 3, 2026. Mark Coleman, Director: sold $8.0M across 2 filings, first filed Feb 27, 2026, last Jun 2, 2026. Mark E. Saad, Director: sold $6.2M across 1 filing, first filed Jan 2, 2026, last Jan 2, 2026. Ari Maizel, Chief Commercial Officer: sold $2.8M across 2 filings, first filed Jan 23, 2026, last Apr 23, 2026.
Largest mark · tap a row for others
Herriot Tabuteau · Chief Executive Officer
Sale $23,881,618
139,414 shares at $171.30 avg
Filed Jan 7, 2026 · traded Jan 5
Pre-arranged (10b5-1) · close on filing date $170.69
Herriot Tabuteau · Chief Executive Officer
Chief Executive Officer
$97.8M soldNick Pizzie · Chief Financial Officer
Chief Financial Officer
$10.2M soldMark L. Jacobson · Chief Operating Officer
Chief Operating Officer
$8.9M soldMark Coleman · Director
Director
$8.0M soldMark E. Saad · Director
Director
$6.2M soldAri Maizel · Chief Commercial Officer
Chief Commercial Officer
$2.8M soldHas Axsome Therapeutics, Inc's CEO sold stock?
Yes. Herriot Tabuteau (CEO) sold 564,736 shares ($97.8M) between Nov 2025 and Aug 2026, all under a pre-arranged 10b5-1 plan.
Open-market trades
17 filings in the last 12 months| Insider | Role | Sold | Bought | Filings | Pre-arranged (10b5-1) | Last filed |
|---|---|---|---|---|---|---|
| Herriot Tabuteau | Chief Executive Officer | $97.8M | — | 7 | 100% of sales | |
| Nick Pizzie | Chief Financial Officer | $10.2M | — | 2 | 100% of sales | |
| Mark L. Jacobson | Chief Operating Officer | $8.9M | — | 3 | 100% of sales | |
| Mark Coleman | Director | $8.0M | — | 2 | 100% of sales | |
| Mark E. Saad | Director | $6.2M | — | 1 | 100% of sales | |
| Ari Maizel | Chief Commercial Officer | $2.8M | — | 2 | 100% of sales |
| Filed | Insider | Type | Shares | Avg price | Value | Held after | Source |
|---|---|---|---|---|---|---|---|
traded | Mark L. Jacobson Chief Operating Officer | SalePre-arranged (10b5-1) | 10,000 | $208.65 | $2.1M | 0 | |
traded | Herriot Tabuteau Chief Executive Officer | SalePre-arranged (10b5-1) | 49,664 | $212.19 | $10.5M | 7,229 | |
traded | Herriot Tabuteau Chief Executive Officer | SalePre-arranged (10b5-1) | 49,666 | $240.25 | $11.9M | 7,229 | |
traded | Nick Pizzie Chief Financial Officer | SalePre-arranged (10b5-1) | 33,000 | $240.09 | $7.9M | 42,867 | |
traded | Herriot Tabuteau Chief Executive Officer | SalePre-arranged (10b5-1) | 49,670 | $241.01 | $12.0M | 7,229 | |
traded | Mark Coleman Director | SalePre-arranged (10b5-1) | 17,537 | $229.20 | $4.0M | 29,603 | |
traded | Mark L. Jacobson Chief Operating Officer | SalePre-arranged (10b5-1) | 4,750 | $227.95 | $1.1M | 0 | |
traded | Ari Maizel Chief Commercial Officer | SalePre-arranged (10b5-1) | 7,500 | $182.42 | $1.4M | 0 | |
traded | Mark L. Jacobson Chief Operating Officer | SalePre-arranged (10b5-1) | 35,378 | $161.88 | $5.7M | 0 | |
traded | Mark Coleman Director | SalePre-arranged (10b5-1) | 25,000 | $161.11 | $4.0M | 47,140 | |
traded | Herriot Tabuteau Chief Executive Officer | SalePre-arranged (10b5-1) | 32,410 | $185.60 | $6.0M | 7,229 | |
traded | Ari Maizel Chief Commercial Officer | SalePre-arranged (10b5-1) | 7,500 | $184.44 | $1.4M | 0 | |
traded | Nick Pizzie Chief Financial Officer | SalePre-arranged (10b5-1) | 12,000 | $187.92 | $2.3M | 42,588 | |
traded | Herriot Tabuteau Chief Executive Officer | SalePre-arranged (10b5-1) | 139,414 | $171.30 | $23.9M | 7,229 | |
traded | Mark E. Saad Director | SalePre-arranged (10b5-1) | 37,577 | $165.18 | $6.2M | 10,002 | |
traded | Herriot Tabuteau Chief Executive Officer | SalePre-arranged (10b5-1) | 79,973 | $145.66 | $11.6M | 7,229 | |
traded | Herriot Tabuteau Chief Executive Officer | SalePre-arranged (10b5-1) | 163,939 | $133.07 | $21.8M | 7,229 |
GET /stocks/filings/vX/form-4?tickers=AXSM&filing_date.gte=2025-10-23&sort=filing_date.desc&limit=500{
"status": "OK",
"results": [
{
"tickers": [
"AXSM"
],
"issuer_cik": "0001579428",
"owner_cik": "0001805812",
"accession_number": "0001193125-26-382277",
"form_type": "4",
"filing_date": "2026-09-03",
"period_of_report": "2026-09-03",
"issuer_name": "Axsome Therapeutics, Inc.",
"issuer_trading_symbol": "AXSM",
"owner_name": "Jacobson Mark L.",
"is_director": false,
"is_officer": true,
"is_ten_percent_owner": false,
"is_other": false,
"officer_title": "Chief Operating Officer",
"security_type": "non_derivative",
"record_type": "transaction",
"security_title": "Common Stock",
"transaction_timeliness": "O",
"aff_10b5_one": true,
"transaction_date": "2026-09-03",
"transaction_code": "S",
"equity_swap_involved": false,
"transaction_shares": 10000,
"transaction_price_per_share": 208.65,
"transaction_acquired_disposed": "D",
"shares_owned_following_transaction": 0,
"transaction_value": 2086500,
"direct_or_indirect": "D",
"footnotes": [
{
"id": "F2",
"description": "Such transaction was pursuant to a pre-approved 10b5-1 plan."
},
{
"id": "F3",
"description": "Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options."
},
{
"id": "F4",
"description": "Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $206.41 and $210.34."
}
]
},
{
"tickers": [
"AXSM"
],
"issuer_cik": "0001579428",
"owner_cik": "0001219927",
"accession_number": "0001193125-26-340688",
"form_type": "4",
"filing_date": "2026-08-07",
"period_of_report": "2026-08-05",
"issuer_name": "Axsome Therapeutics, Inc.",
"issuer_trading_symbol": "AXSM",
"owner_name": "TABUTEAU HERRIOT",
"is_director": true,
"is_officer": true,
"is_ten_percent_owner": true,
"is_other": false,
"officer_title": "Chief Executive Officer",
"security_type": "non_derivative",
"record_type": "transaction",
"security_title": "Common Stock",
"transaction_timeliness": "O",
"aff_10b5_one": true,
"transaction_date": "2026-08-06",
"transaction_code": "S",
"equity_swap_involved": false,
"transaction_shares": 4660,
"transaction_price_per_share": 213.95,
"transaction_acquired_disposed": "D",
"shares_owned_following_transaction": 7229,
"transaction_value": 997007,
"direct_or_indirect": "D",
"footnotes": [
{
"id": "F2",
"description": "Such transaction was pursuant to a pre-approved 10b5-1 plan, which has now been completed."
},
{
"id": "F3",
"description": "Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options."
},
{
"id": "F5",
"description": "Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $212.41 and $216.36."
}
]
}
]
}
// trimmed to 2 resultsThe response includes every Form 4 record; this page keeps open-market purchases and sales on common stock and removes duplicate joint-filer rows.
Other insider activity (not market trades) · 36 records
- Option exercises31 records
- Tax withholding (sold to cover)5 records
Reported on Form 4 but not purchases or sales in the market, so not counted in the totals above.
Build this yourself
This page joins two Massive endpoints: Form 4 filings and daily prices. Ask an agent to watch for new filings:
Using the Massive API (massive.com/docs/llms.txt), check Form 4 filings for AXSM every day with transaction_code=P and tell me when an insider files an open-market purchase, with their role, shares, price and the filing link.
How to read this page
- Open-market purchase or sale
- A buy or sell of the company's stock at market price. Grants, option exercises, shares withheld for tax, gifts and employee stock plan purchases are listed separately and not counted.
- Pre-arranged (10b5-1)
- The insider marked the filing as made under a trading plan set up in advance (SEC Rule 10b5-1). The mark covers the whole filing, and an unmarked filing may still be under a plan.
- Filing date
- Insiders have two business days to report a trade. Totals and the chart use the filing date, when the trade became public.