Ionis Pharmaceuticals, Inc. (IONS) insider trading

{
  "status": "OK",
  "results": [
    {
      "tickers": [
        "IONS"
      ],
      "issuer_cik": "0000874015",
      "owner_cik": "0001791058",
      "accession_number": "0000874015-26-000266",
      "form_type": "4",
      "filing_date": "2026-10-19",
      "period_of_report": "2026-10-15",
      "issuer_name": "IONIS PHARMACEUTICALS INC",
      "issuer_trading_symbol": "IONS",
      "owner_name": "Swayze Eric",
      "is_director": false,
      "is_officer": true,
      "is_ten_percent_owner": false,
      "is_other": false,
      "officer_title": "EVP Research",
      "security_type": "non_derivative",
      "record_type": "transaction",
      "security_title": "Common Stock",
      "transaction_timeliness": "O",
      "aff_10b5_one": false,
      "transaction_date": "2026-10-16",
      "transaction_code": "S",
      "equity_swap_involved": false,
      "transaction_shares": 53,
      "transaction_price_per_share": 43.5389,
      "transaction_acquired_disposed": "D",
      "shares_owned_following_transaction": 390,
      "transaction_value": 2307.5616999999997,
      "not_subject_to_section_16": false,
      "direct_or_indirect": "I",
      "nature_of_ownership": "by Son",
      "footnotes": [
        {
          "id": "F2",
          "description": "The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice."
        }
      ]
    },
    {
      "tickers": [
        "IONS"
      ],
      "issuer_cik": "0000874015",
      "owner_cik": "0002037721",
      "accession_number": "0000874015-26-000267",
      "form_type": "4",
      "filing_date": "2026-10-19",
      "period_of_report": "2026-10-15",
      "issuer_name": "IONIS PHARMACEUTICALS INC",
      "issuer_trading_symbol": "IONS",
      "owner_name": "Devers Shannon L.",
      "is_director": false,
      "is_officer": true,
      "is_ten_percent_owner": false,
      "is_other": false,
      "officer_title": "EVP, Chief Human Resources Ofc",
      "security_type": "non_derivative",
      "record_type": "transaction",
      "security_title": "Common Stock",
      "transaction_timeliness": "O",
      "aff_10b5_one": false,
      "transaction_date": "2026-10-16",
      "transaction_code": "S",
      "equity_swap_involved": false,
      "transaction_shares": 1357,
      "transaction_price_per_share": 43.5386,
      "transaction_acquired_disposed": "D",
      "shares_owned_following_transaction": 17811,
      "transaction_value": 59081.88020000001,
      "not_subject_to_section_16": false,
      "direct_or_indirect": "D",
      "footnotes": [
        {
          "id": "F2",
          "description": "The sale was made pursuant to an automatic sale to cover the required tax withholding obligations pursuant to the 2011 Equity Incentive Plan Restricted Stock Unit Agreement and Grant Notice."
        },
        {
          "id": "F3",
          "description": "The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $43.1383 to $43.538918 inclusive.  The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4."
        }
      ]
    }
  ]
}

// trimmed to 2 results

The response includes every Form 4 record; this page keeps open-market purchases and sales on common stock and removes duplicate joint-filer rows.